Email this article A novel molecular approach in the study of parasite-host interaction
Abstract
Effectors have become the cornerstone of all investigations related to the interaction of parasites and their hosts, how they regulate the processes of infection at a molecular level, and how these molecules have evolved seem to be the most important issues that will have to be addressed in the following years. These new lines of research will be subject to the enormous progress that the next generation of sequencing technologies will have, and with them a paradigm shift in our vision of complex systems. However, there remain many questions to be elucidated about effectors, for example, how these proteins interact spatially and temporally in their hosts, possible co-operation between effectors, and the existence of protein complexes within host cells. This leads to the following questions: Do the effectors have the capacity for phenotypic expression beyond the genes that encode them? And above all, why are these proteins so widespread on a huge range of evolutionarily distant pathogens?
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DOI: http://dx.doi.org/10.18781/R.MEX.FIT.1808-6
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